Lorlatinib (PF-06463922) is an oral active, selective, brain osmotic and ATP-competitive ROS1/ALK inhibitor. The Ki of Lorlatinib for ROS1, wild-type ALK and ALK(L1196M) were <0.025 nM, <0.07 nM and 0.7 nM, respectively. Lorlatinib has anticancer activity.
Molecular Weight:
406.41
Purity:
99.52%
CAS Number:
[1454846-35-5]
Formula:
C21H19FN6O2
Target:
ALK
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