TP0472993 is a novel, orally active, selective inhibitor of 20-hydroxyeicosatetraenoic acid (20-HETE) synthesis that inhibits the production of 20-HETE, thereby reducing the ERK1/2 and STAT3 signaling pathways, and ultimately inhibiting the progression of renal fibrosis. It can be used in studies related to chronic kidney disease (CKD).
Molecular Weight:
300.36
Purity:
>98.5%
CAS Number:
[2126874-77-7]
Formula:
C16H20N4O2
Target:
Cytochrome P450 (e.g. CYP17)
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