Ritlecitinib tosylate is a first-in-class, orally active, dual covalent inhibitor of tyrosine kinases in the JAK3 and TEC families. The IC50 for JAK3 is 33.1 nM and there is no activity against JAK1, JAK2 and TYK2.
Molecular Weight:
457.55
Purity:
>99.0%
CAS Number:
[2192215-81-7]
Formula:
C22H27N5O4S
Target:
JAK
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