TIM-3-IN-2 is a Tim3 inhibitor (KD: 0.61 µM). TIM-3-IN-2 inhibits the immunosuppressive function of TIM-3. TIM-3-IN-2 reverses the TIM-3-mediated blockade of the production of proinflammatory cytokines, and maximizes the T-cell antitumor activity against AML cell lines.
Molecular Weight:
461.47
Purity:
99.0%
CAS Number:
[1113126-49-0]
Formula:
C25H23N3O6
Target:
Others
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