Shikonin (C.I. 75535, Anchusin, Anchusa acid, Alkanna Red, Isoarnebin 4, NSC 252844) is an effective and specific inhibitor of Pyruvate kinase M2 (PKM2). Shikonin is the main ingredient of Lithosia, a Chinese herb with a variety of biological activities. Shikonin acts as an anti-inflammatory by inhibiting tumor necrosis factor-alpha (TNF-alpha), Proteasome can inhibit the activation of nuclear factor-kappaB (NF-kappaB) signaling pathway.
Molecular Weight:
288.30
Purity:
99.58%
CAS Number:
[517-89-5]
Formula:
C16H16O5
Target:
TNF Receptor
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