Oroxylin A is an active flavonoid that inhibits the phosphorylation of MDM2 and SIRT1 through the inhibition of CDK9, thus inhibiting MDM2-mediated degradation of P53 and SIRT1-mediated deacetylation of P53, and ultimately stabilizing the P53 protein.Oroxylin A has strong anticancer activity.
Molecular Weight:
284.26
Purity:
99.47%
CAS Number:
[480-11-5]
Formula:
C16H12O5
Target:
CDK
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