Irinotecan is an inhibitor of Topoisomerase I, preventing religation of the DNA strand by binding to topoisomerase I-DNA complex. Irinotecan inhibits the growth of LoVo and HT-29 cells, with IC50s of 15.8 5.1 and 5.17 1.4 µM, respectively.
Molecular Weight:
586.68
Purity:
99.58%
CAS Number:
[97682-44-5]
Formula:
C33H38N4O6
Target:
Topoisomerase
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