Lifitegrast sodium is a potent integrin antagonist that blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen (LFA-1) and interrupts the T cell-mediated inflammatory cycle. Lifitegrast sodium inhibits the attachment of Jurkat T cells to ICAM-1 with an IC50 of 2.98 nM.May be useful in studies related to dry eye.
Molecular Weight:
637.46
Purity:
>99.0%
CAS Number:
[1119276-80-0]
Formula:
C29H23Cl2N2NaO7S
Target:
Integrin
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