Zamaporvint is an orally active, selective Wnt inhibitor that targets the membrane-bound o-acyltransferase porcupine and inhibits Wnt ligand palmitoylation, secretion and pathway activation. In addition, Zamaporvint displays potent antiproliferative effects in Wnt ligand-dependent colorectal and pancreatic cell lines. It can be used in cancer-related studies.
Molecular Weight:
439.39
Purity:
>99.0%
CAS Number:
[1900754-56-4]
Formula:
C21H16F3N7O
Target:
Wnt/beta-catenin
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