BAY87-2243 is a potent inhibitor of selective hypoxia-inducible facin-1 (HIF-1). Bay87-2243 induces iron death and necrosis in BRAFV600E melanoma cells by inhibiting the mitochondrial respiratory chain, resulting in ROS accumulation, lipid peroxidation, and GSH deletion.
Molecular Weight:
525.53
Purity:
98.86%
CAS Number:
[1227158-85-1]
Formula:
C26H26F3N7O2
Target:
HIF
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