RNA Synthesis IN-1 (a substitute for Actinomycin D) is an inhibitor of RNA and protein synthesis, with antibacterial and anti-tumor effects. RNA Synthesis IN-1 can inhibit the protein synthesis of bacteria, directly bind to the guanine groups of single-stranded or double-stranded DNA in the transcriptional initiation complex, inhibit the activity of DNA-dependent RNA polymerase, and interfere with the transcription process of DNA, thereby inhibiting mRNA synthesis. RNA Synthesis IN-1 inhibits DNA repair with an IC50 value of 0.42 µM.
Molecular Weight:
1255.5
Purity:
99.0%
CAS Number:
[50-76-0]
Formula:
C62H86N12O16
Target:
DNA/RNA Synthesis
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