Cabozantinib malate (XL184) is the malate of Cabozantinib, a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM in cell-free assays, respectively.
Molecular Weight:
635.59
Purity:
>99.0%
CAS Number:
[1140909-48-3]
Formula:
C28H24FN3O5.C4H6O5
Target:
VEGFR/PDGFR
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