AZ5104, the demethylated metabolite of AZD-9291, is a potent EGFR inhibitor with IC50 of <1 nM, 6 nM, 1 nM, and 25 nM for EGFR (L858R/T790M), EGFR (L858R), EGFR (L861Q), and EGFR (wildtype), respectively.
Molecular Weight:
485.58
Purity:
>99.0%
CAS Number:
[1421373-98-9]
Formula:
C27H31N7O2
Target:
FGFR
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