Zamicastat is a dopamine beta-hydroxylase (DBH) inhibitor that crosses the blood-brain barrier and causes central and peripheral effects. In addition, Zamicastat is a concentration-dependent dual P-gp and BCRP inhibitor with IC50 values of 73.8 µM and 17.0 µM, respectively.
Molecular Weight:
401.47
Purity:
>98.0%
CAS Number:
[1080028-80-3]
Formula:
C21H21F2N3OS
Target:
BCRP/ABCG2/MXR/ABCP
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