UNC2025 is a potent, ATP-competitive and highly orally active Mer/Flt3 inhibitor with IC50 values of 0.74 nM and 0.8 nM, respectively. UNC2025 is >45-fold selectivity for MERTK relative to Axl (IC50= 122 nM, Ki = 13.3 nM). UNC2025 exhibits an excellent PK properties.
Molecular Weight:
476.66
Purity:
>99%
CAS Number:
[1429881-91-3]
Formula:
C28H40N6O
Target:
FLT3
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