GSK481 is a highly effective, selective and specific RIPK1 inhibitor with an IC50 value of 1.3 nM, which can inhibit the phosphorylation of Ser166 in wild-type human RIPK1 (IC50 value of 2.8 nM). The IC50 value of GSK481 against U937 cells was 10 nM.
Molecular Weight:
377.39
Purity:
99.90%
CAS Number:
[1622849-58-4]
Formula:
C21H19N3O4
Target:
RIPK
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