EED226 is an effective, selective and orally active Polycomb reactive complex 2 (PRC2) inhibitor. When h3k27me0 peptide is used as substrate, ic50=23.4 nm, With mononucleosome as substrate, ic50=53.5 nm. It is a first in class, effective, orally bioavailable inhibitor of embryonic ectodermal development (EED) with strong anticancer effect.
Molecular Weight:
369.40
Purity:
>99.0%
CAS Number:
[2083627-02-3]
Formula:
C17H15N5O3S
Target:
PRC2/EED
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