E7449, CAS [[1140964-99-3]]

Product Overview

• Article Name: E7449, CAS [[1140964-99-3]]
• Biozol Catalog Number: AMO-M5267
• Supplier Catalog Number: M5267
• Alternative Catalog Number: AMO-M5267-5MG,AMO-M5267-10MG,AMO-M5267-25MG,AMO-M5267-50MG,AMO-M5267-100MG
• Manufacturer: Abmole Bioscience
• Category: Biochemikalien
• Alternative Names: Stenoparib, 2X-121, MGI25036

Product Description

E7449 is an orally bioavailable, brain penetrable, small molecule dual inhibitor of PARP1/2 that also inhibits PARP5a/5b, otherwise known as tankyrase1 and 2 (TNKS1/2), important regulators of canonical Wnt/beta-catenin signaling. It has IC50 values of 1.0 and 1.2 nM for PARP1 and 2, respectively.

Product Properties

• Molecular Weight: 317.34
• Purity: >98%
• CAS Number: [1140964-99-3]
• Formula: C18H15N5O
• Target: PARP