GSK180736A, developed as a Rho-associated, coiled-coil-containing protein kinase inhibitor, binds to GRK2(G protein-coupled receptor kinase 2) with logIC50 pf -6.6 (logIC50 -4.0 for GRK5 and >-3 for GRK1), 400-fold selective for GRK2 over both GRK1 and GRK5.
Molecular Weight:
365.36
Purity:
>98.0%
CAS Number:
[817194-38-0]
Formula:
C19H16FN5O2
Target:
ROCK
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