Nazartinib (EGF816, NVS-816) is a covalent, irreversible, mutant-selective EGFR inhibitor that has nanomolar inhibitory potency against activating mt (L858R, ex19del) and T790M mt, with up to 60-fold selectivity over wild type (wt) EGFR in vitro.
Molecular Weight:
495.02
Purity:
>99.0%
CAS Number:
[1508250-71-2]
Formula:
C26H31ClN6O2
Target:
EGFR/HER2
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