Afatinib dimaleate, CAS [[850140-73-7]]

Product Overview

• Article Name: Afatinib dimaleate, CAS [[850140-73-7]]
• Biozol Catalog Number: AMO-M5307
• Supplier Catalog Number: M5307
• Alternative Catalog Number: AMO-M5307-10MG,AMO-M5307-50MG,AMO-M5307-200MG
• Manufacturer: Abmole Bioscience
• Category: Biochemikalien
• Alternative Names: BIBW 2992MA2, BIBW2992, Afatinib

Product Description

Afatinib (BIBW2992) Dimaleate irreversibly inhibits EGFR/HER2 including EGFR(wt), EGFR(L858R), EGFR(L858R/T790M) and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively, 100-fold more active against Gefitinib-resistant L858R-T790M EGFR mutant.

Product Properties

• Molecular Weight: 717.18
• Purity: 100.00%
• CAS Number: [850140-73-7]
• Formula: C24H25ClFN5O3.2C4H4O4
• Target: EGFR/HER2