Crizotinib is inhibitor of the c-Met kinase and the NPM-ALK. Crizotinib inhibited cell proliferation in ALK-positive ALCL cells (IC50s=30 nM). Crizotinib is useful in treatment of anaplastic large-cell lymphoma.
Molecular Weight:
486.8
Purity:
>99.0%
CAS Number:
[1415560-69-8]
Formula:
C21H23Cl3FN5O
Target:
ALK
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