Motesanib (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 2 nM/3 nM/6 nM, respectively, similar activity against Kit, ~10-fold more selective for VEGFR than PDGFR and Ret.
Molecular Weight:
373.45
Purity:
>99.0%
CAS Number:
[453562-69-1]
Formula:
C22H23N5O
Target:
c-Kit
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