WZ3146 is a mutant-selective irreversible inhibitor of EGFR(L858R) and EGFR(E746_A750) with IC50 of 2 nM and 2 nM, does not inhibit ERBB2 phosphorylation (T798I).
Molecular Weight:
464.95
Purity:
>99.0%
CAS Number:
[1214265-56-1]
Formula:
C24H25ClN6O2
Target:
EGFR/HER2
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