Mercaptopurine inhibits purine nucleotide synthesis and metabolism by inhibiting phosphoribose pyrophosphate amide transferase (PRPP amide transferase). PRPP amide transferase is a rate-limiting enzyme formed by purine. It alters the synthesis and function of RNA and DNA. Mercaptopurine also interferes with nucleoside tautomies and glycoprotein synthesis.
Molecular Weight:
170.19
Purity:
>99.0%
CAS Number:
[6112-76-1]
Formula:
C5H6N4OS
Target:
DNA/RNA Synthesis
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