K41498 TFA is an antisauvagine-30 (aSvg-30) analog and a strongly selective CRF2 receptor antagonist with Ki values of 0.66 nM, 0.62 nM, and 425 nM for human CRF2alpha, CRF2beta, and CRF1 receptors, respectively.K41498 TFA inhibits sauvagine-stimulated cAMP accumulation in hCRF2alpha/hCRF2beta expressing cells. K41498 TFA can be used in hypotension studies.
Molecular Weight:
3632.20 (free base)
Purity:
>98.0%
CAS Number:
[434938-41-7free base]
Formula:
C162H276N48O46.xC2HF3O2
Target:
CRFR
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