NST-628 is a brain-permeable MAPK pathway molecule glue that inhibits RAF phosphorylation and MEK activation. NST-628 also binds RAF and prevents the formation of BRAF-CRAF and BRAF-ARAF heterodimers, effectively inhibiting the RAS-MAPK pathway.
Molecular Weight:
488.46
Purity:
>98.5%
CAS Number:
[3002056-30-3]
Formula:
C22H18F2N4O5S
Target:
Raf
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