VVD-214 (RO7589831) is a synthetic lethal allosteric inhibitor of WRN helicase. VVD-214 covalently binds to cysteine 727 of WRN and inhibits ATP hydrolysis and helicase activity.
Molecular Weight:
437.46
Purity:
>99.0%
CAS Number:
[3026500-20-6]
Formula:
C20H21F2N3O4S
Target:
DNA/RNA Synthesis
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