PT-179 is an orthogonal Thalidomide (M2225) derivative that targets cereblon without causing off-target degradation effects. PT-179 is able to specifically bind CRBN, form a ternary complex with a target protein fused to a zinc finger (ZF) degron, and mediate the degradation of the tagged protein.
Molecular Weight:
343.33
Purity:
100.0%
CAS Number:
[2924858-25-1]
Formula:
C17H17N3O5
Target:
Ligand for E3 Ligase
* VAT and and shipping costs not included. Errors and price changes excepted