Embelin is a cell-permeable benzoquinone compound that exhibits antitumor properties. Specifically antagonizes XIAP-mediated inhibition of caspase-9 activation by directly targeting the Smac and caspase-9 binding domain BIR3 (IC50 = 4.1 uM in a competitive binding assay with Smac peptide).
Molecular Weight:
294.39
Purity:
>98.5%
CAS Number:
[550-24-3]
Formula:
C17H26O4
Target:
IAP
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