Calphostin C (PKF115-584) is a small molecule inhibitor of Wnt/beta-catenin/lef-1 signaling. Calphostin C is also a potent and specific inhibitor of protein kinase C. PKF115-584 efficiently killed CLL cells (LC(50)<1 microM), whereas normal B cells were not significantly affected.
Molecular Weight:
790.76
Purity:
99.0%
CAS Number:
[121263-19-2]
Formula:
C44H38O14
Target:
Wnt/beta-catenin
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