ASK1-IN-1 is a novel CNS-penetrant apoptosis signal-regulating kinase 1 (ASK1) inhibitor with good potency (cell IC50 = 138 nM), low clearance (rat Cl/Clu = 0.36/6.7 L h-1 kg-1) and good CNS penetration (rat K p,uu = 0.38).
Molecular Weight:
405.41
Purity:
99.0%
CAS Number:
[2411382-24-4]
Formula:
C19H19N9O2
Target:
MAPKAPK2/MAP3K/MAP4K
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