SR-4995 is a potent and selective ligand of alpha-beta-hydrolase domain containing 5 (ABHD5) that activates adipose triglyceride lipase (ATGL) by dissociating ABHD5 from its inhibitory regulator, perilipin-1 (PLIN1) and PLIN5. SR-4995 directly binds to ABHD5 and prevents ABHD5 to PLIN1. SR-4995 induces lipolysis in adipocytes and muscle, avoiding PKA-dependent signaling.
Molecular Weight:
355.45
Purity:
98.0%
CAS Number:
[891509-95-8]
Formula:
C19H21N3O2S
Target:
Metabolite/Endogenous Metabolite
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