CDDO-TFEA (RTA 404, TP-500) is a trifluoroacetamide derivative of CDDO with enhanced ability to cross the blood-brain barrier. CDDO is an Nrf2 activator that inhibits proliferation and induces differentiation and apoptosis in various cancer cells. CDDO-TFEA can enhance Nrf2 expression and signaling in various neurodegenerative disease models.
Molecular Weight:
572.7
Purity:
>98.0%
CAS Number:
[932730-52-4]
Formula:
C33H43F3N2O3
Target:
Keap1-Nrf2
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