Lifitegrast is an antagonist of integrin lymphocyte function associated antigen-1 (LFA-1). The IC50 of Jurkat T cells to icAM-1 was 2.98nM. Lifitegrast blocks the interaction between LFA-1 and ICAM-1, thereby reducing T cell activity and cytokine secretion.
Molecular Weight:
615.48
Purity:
99.81%
CAS Number:
[1025967-78-5]
Formula:
C29H24Cl2N2O7S
Target:
Integrin
* VAT and and shipping costs not included. Errors and price changes excepted