CHR-6494 TFA is a potent and selective inhibitor of haspin, with an IC50 of 2 nM. CHR-6494 TFA induces cell cycle arrest at G2/M, inhibits cell proliferation, and promotes apoptosis in multiple cancer cell lines. CHR-6494 TFA inhibits histone H3T3 phosphorylation.
Molecular Weight:
406.36
Purity:
98.0%
CAS Number:
[1458630-17-5]
Formula:
C18H17F3N6O2
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