ATRA, Tretinoin, Vitamin A acid, all-trans-Retinoic acid
Retinoic acid is A metabolite of vitamin A and plays an important role in cell growth, differentiation and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors with an IC50 of 14 nM for RARalpha/beta/gamma. The Kd value of Retinoic acid combined with PPARbeta/delta is 17 nM. Retinoic acid inhibits the transcription factor Nrf2 by activating Retinoic acid receptors.
Molecular Weight:
300.44
Purity:
>99.0%
CAS Number:
[302-79-4]
Formula:
C20H28O2
Target:
PPAR
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