EAI045 is a fourth generation allosteric inhibitor of mutant EGFR, which inhibits EGFR at 10 µM ATP, EGFRL858R, EGFRT790M and EGFRL858R/T790M with IC50 values of 1.9, 0.019, 0.19 and 0.002 µM respectively.
Molecular Weight:
383.40
Purity:
>98%
CAS Number:
[1942114-09-1]
Formula:
C19H14FN3O3S
Target:
EGFR/HER2
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