Adaptaquin is a hIF-prolyl hydroxylase-2 (PHD2) inhibitor. Adaptaquin blocks glutamate induced ROS production in HT-22 cells, independent of MnSOD. Adaptaquin exhibits neuroprotective effects and enhances functional recovery in rodent intracerebral hemorrhage models, via inhibition of ATF4 dependent genes. Brain penetrant. Also antioxidant.
Molecular Weight:
377.82
Purity:
>99.0%
CAS Number:
[385786-48-1]
Formula:
C21H16ClN3O2
Target:
Others
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