Ciglitazone is an effective selective PPARgamma agonist (EC50=3 µM). Ciglitazone inhibited the proliferation and differentiation of TH17 cells. Ciglitazone is an oral hypoglycemic agent that has been shown to be active in obese hyperglycemic animal models. Ciglitazone induces apoptosis in opossum renal epithelial cells and simultaneously activates nuclear translocation of P38 MAPK and apoptosis-inducing factor (AIF).
Molecular Weight:
333.44
Purity:
>98%
CAS Number:
[74772-77-3]
Formula:
C18H23NO3S
Target:
PPAR
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