CZC 25146 is a potent and orally active LRRK2 inhibitor with IC50 values of 4.76 nM and 6.87 nM for wild-type LRRK2 and G2019S LRRK2, respectively. CZC-25146 inhibits PLK4, GAK, TNK1, CAMKK2 and PIP4K2C as well.
Molecular Weight:
488.54
Purity:
>98.5%
CAS Number:
[1191911-26-8]
Formula:
C22H25FN6O4S
Target:
LRRK2
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