ML171 is a potent and selective inhibitor of NADPH-oxidase with IC50s of 0.25 µM, 5 µM, 3µM, 5 µM and 5.5 µM for NOX1, NOX2, NOX3, NOX4 and xanthine oxidase, respectively. ML171 (2-Acetylphenothiazine,2-APT) is a potent and selective NADPH oxidase 1 (Nox1) inhibitor that blocks Nox1-dependent ROS generation, with an IC50 of 0.25 µM in HEK293-Nox1 confirmatory assay.
Molecular Weight:
241.31
Purity:
98.85%
CAS Number:
[6631-94-3]
Formula:
C14H11NOS
Target:
NADPH Oxidase
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