Pladienolide B is a potent pre-mRNA splicing inhibitor, exerts antitumor activities mediated through the inhibition of pre-mRNA splicing. Pladienolide B is a potent cancer cell growth inhibitor that targets the SF3B1 subunit of the spliceosome. Pladienolide B induces apoptosis.
Molecular Weight:
536.7
Purity:
>99%
CAS Number:
[445493-23-2]
Formula:
C30H48O8
Target:
Apoptosis
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