Meclinertant (SR 48692) is an effective, selective, non-peptide and oral antagonist of active neurotensin receptor (NTS1). Meclinertant competitively antagonizes neurotensin-induced intracellular Ca2+ mobilization in human colon cancer cells, with a pA2 value of 8.13. Meclinertant has anti-anxiety, anti-addiction and memory disorder effects.
Molecular Weight:
587.07
Purity:
>98%
CAS Number:
[146362-70-1]
Formula:
C32H31ClN4O5
Target:
Neurotensin Receptor
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