MCC950 (CP-456773) sodium salt is a potent, selective NLRP3 inhibitor with IC50s of 7.5 and 8.1 nM in BMDMs and HMDMs, respectively. MCC950 specifically inhibits NLRP3 but not AIM2, NLRC4 or NLRP1 activation.
Molecular Weight:
426.46
Purity:
99.96%
CAS Number:
[256373-96-3]
Formula:
C20H23N2NaO5S
Target:
Pyroptosis
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