SB-328437 is a potent, selective non-peptide CCR3 antagonist with an IC50 of 4.5 nM. SB 328437 inhibits the recruitment and migration of eosinophils in allergen models of models. SB 328437 suppresses the Th2-mediated eosinophil infiltration in the airways.
Molecular Weight:
378.38
Purity:
>98.0%
CAS Number:
[247580-43-4]
Formula:
C21H18N2O5
Target:
CCR
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