Ro 25-6981 maleate salt is a potent and selective antagonist of NMDA glutamate receptors containing the NR2B subunit with IC50 values of .009 µM for NR2B vs. 52 µM for NR2A subunits. Ro 25-6981 has been shown to have neuroprotectant effects and to reduce inflammatory and neuropathic pain in rodent models.
Molecular Weight:
455.54
Purity:
98.13%
CAS Number:
[1312991-76-6]
Formula:
C22H29NO2.C4H4O4
Target:
GluR
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