Brusatol (NSC 172924) is a plant-derived natural quassinoid that exhibits broad cytotoxicity in cancer cultures (IC50 <1 µM against 457 cancer cell lines) by inhibiting de novo synthesis of cellular proteins (Effective conc. <50 nM in A549 cells), including NRF2.
Molecular Weight:
520.53
Purity:
>99.0%
CAS Number:
[14907-98-3]
Formula:
C26H32O11
Target:
Keap1-Nrf2
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