Necrosulfonamide is a necroptosis inhibitor which selectively targeting the mixed lineage kinase domain-like protein (MLKL) with IC50 value of 124 nM in human HT-29. Necrosulfonamide prevents MLKL-RIP1-RIP3 necrosome complex from interacting with its downstream effectors.
Molecular Weight:
461.47
Purity:
>99%
CAS Number:
[1360614-48-7]
Formula:
C18H15N5O6S2
Target:
Necroptosis
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