Z-Guggulsterone is a mineralocorticoid, progesterone and glucocorticoid receptor antagonist (Ki values are 37, 224 and 252 nM respectively) and weak androgen receptor agonist (Ki = 315 nM). (Z)-Guggulsterone is also a potent FXR antagonist. (Z)-Guggulsterone reduces ACE2 expression and SARS-CoV-2 infection.
Molecular Weight:
312.45
Purity:
99.33%
CAS Number:
[39025-23-5]
Formula:
C21H28O2
Target:
Farnesoid X Receptor
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